Solid phase Peptide Synthesis

All products available against order or for contract manufacture
Orange : Introduced by Bharavi Labs
Green : Available ex-stock or at short notice

Name : Wang resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Peptide synthesis by Fmoc strategy

Cleavage : 50% TFA-DCM

Name : Wang chloride resin

Technical Information

1% 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Solid phase organic synthesis

Cleavage : TFA-DCM

Name : Wang chloride resin

Technical Information

1% 100-200 or 200-400 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Solid phase organic synthesis

Cleavage : TFA-DCM

Name : Brominated Wang resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Photolabile linker for library generation

Cleavage: Exposure to UV light

References : S. Wang, JOC, 1976, 41, 3256

Name : Brominated PPOA resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage:Peptide synthesis by Boc strategy

Cleavage : Strong acids like HF

References : A. R. Mitchell, et al. JOC, 1978, 43, 2845

Name : 3-Methoxy Wang resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : SPOS

Cleavage : Acid sensitive

References : M. Mergler etal, TL, 1998, 29, 4009

Name : Barlos (2-Chlorotrityl chloride) resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Use : Popular peptide synthesis resin esp. proline & cysteine

Cleavage : CHCl3:EtOH:AOAc

See also amino acids linked to 2-chlorotrityl resin

Name : Merrifield Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

Loading : ~1.2 mmol/g; also offered : 0.6; 2.4; 3.6 mmol/g

Usage : Extensively used core resin for solid phase peptide synthesis and as core resin for other resins

Name : PAM alcohol

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage:Peptide synthesis by Boc strategy

Cleavage : Strong acids like HF

References : A. R. Mitchell, et al. JOC, 1978, 43, 2845

Name : PAM bromide

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage:Peptide synthesis by Boc strategy

Cleavage : Strong acids like HF

References : A.R. Mitchell etal, JOC, 1978, 43, 2845

Name : HMBA-AM Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

0.9-1.2 mmol/g or as required

Usage : Preparation of cyclic peptides; peptide esters, etc.

Cleavage : Nucleophiles

References : R.C. Shephard etal, IJPPR, 1982, 20, 451

Name : HMBA-MBHA Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

0.9-1.2 mmol/g or as required

Usage : Preparation of cyclic peptides, peptide esters, etc.

Cleavage : Nucleophiles

Ref. S.M. Hutchins etal, TL, 1996, 37, 4869+C8

Name : 2-Chlorobenzhydrol resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Immobilisation of carboxylic acids

Cleavage : 30% TFA/DCM

References : K. Barlos etal, Ann, 1981, 951.

Name : Kaiser oxime resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Use : Syn. of carboxamides, hydrazides, hydroxamic acids

Cleavage : Anilines, hydrazines, hydroxylamine derrivatives

Ref.:W.F. Grado & E.T. Kaiser, JOC, 1980, 45, 1295; 1982, 47, 3258; ii) T. Sasaki etal, JOC, 1991, 56, 3159

Name : Rink acid resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Peptide synthesis for acids

Cleavage : 1% TFA-DCM

References : M. Nimizu etal, T, 1994, 50, 2691

Name : Rink acid resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

0.6 ± 0.2 mmol/g or as required

Usage : Peptide synthesis for acids

Cleavage : 1% TFA-DCM

References : H. Rink, TL, 1987, 28, 3787

Name : Knorr 2-CT Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

0.6 ± 0.2 mmol Fmoc/g or as required

Usage : Syn. of carboxamides by fragment condensation

Cleavage : Mild acids

Ref. T. Tselios, et al., J.Med. Chem., 1999, 42, 1170-77

Name : Rink Amide MBHA (Knorr) Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

0.6 ± 0.2 mmol Fmoc/g or as required

Usage : Syn. of carboxamides & sulfonamides

Cleavage : TFA

References :S. C. Story, IJPPR, 1992, 39, 87

Name : Rink Amide AM Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

0.6 ± 0.2 mmol Fmoc/g or as required

Usage : Syn. of carboxamides & sulfonamides

Cleavage : TFA

References :S. C. Story, IJPPR, 1992, 39, 87

Name : Sieber Amide Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Protected peptide amides

Cleavage : 1% TFA

References : i) P. Sieber, TL, 1987, 28, 2107.

Name : Sieber Ethylamide Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Preparation of peptide ethylamines

Cleavage : 1% TFA

References : W.C. Chan etal, JCS-CC, 1995, 1475

Name : Wang chloride resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Solid phase organic synthesis

Cleavage : TFA-DCM

References : W.C. Chan etal, JCS-CC, 1995, 1475

Name : Ramage Resin

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Peptide amides of terminal Phe, Tyr, Ile

Cleavage : 1% TFA

Ref. R. Ramage, et al., TL, 1993, 34, 6599

Name : Benzhydrylamine HCl PS

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Preparation of peptide amides by BOC stretagy

Cleavage : HF or TFMSA

References : G.R. Matsuede etal, Peptides, 1981, 2, 45

Name: Methylbenzhydrylamine HCl PS

Technical Information

1% cross-linked, 100-200 mesh; inquire for other specs.

1.0 ± 0.2 mmol/g or as required

Usage : Prepn of peptide amides, more acid labile than BHA

Cleavage : HF or TFMSA

References : G.R. Matsuede etal, Peptides, 1981, 2, 45

Disclaimer : Products under patents are offered for sale only in those countries where patents have expired.